Most often, it is located in the gingival papilla between adjacent teeth. It is a reactive lesion of connective tissue and is not the softtissue counterpart of central ossifying fibroma. They are firm, nodular, slow growing, spherical non neoplastic tumors. Cementoossifying fibroma cof is considered by most as relatively rare, benign, nonodontogenic neoplasm of the jaw bones and other. Considerable confusion has prevailed in the nomenclature of peripheral ossifying fibroma with various synonyms being used, such as peripheral cementifying fibroma, ossifying fibroepithelial polyp, peripheral fibroma with osteogenesis. The lesion occurs over a wide age range with females being affected more often than males. Females are more commonly affected than males, and anterior maxilla is the most prevalent location of. Peripheral ossifying fibroma pof is a nonneoplastic entity, which occurs on the gingiva in response to trauma or irritation. Peripheral ossifying fibroma pof exclusively found on the gingiva and may be presented with randomly distributed calcifications, immature bone, separation of teeth and bone resorption. Peripheral ossifying fibroma is a fairly common lesion, representing % of all oral biopsies in most series. Females are more commonly affected than males, and the anterior maxilla is the most common site of.
He also suggested that the name peripheral ossifying fibroma should be retained for this lesion. An unusual presentation of peripheral ossifying fibroma in. The histomorphogenic spectrum of peripheral ossifying fibroma. Peripheral ossifying fibroma pof is a reactive overgrowth occurring frequently in anterior maxilla originating from connective tissue or periodontal ligament. Peripheral ossifying fibroma was first identified as a lesion by shephard in 1844 1 and eversole and rovin 3 gave it its current nomenclature along with highlighting its similarities with pyogenic granuloma, peripheral giant cell granuloma or ossifying fibroma all of which are reactive intraoral lesions developing in response to local irritants. Ossifying fibroma has the propensity to occur in cranial bones, but the peripheral variety shows a close relationship with the periodontal ligament and adjacent alveolar bone.
This paper is a case report of a peripheral ossifying fibroma removal in the interproximal area of teeth 21 and 22 in addition to root coverage of the affected area through two surgical phases. Peripheral ossifying fibroma definition of peripheral. The peripheral odontogenic fibroma is an uncommon gingival mass. Jof, also known as psammomatoid or juvenile active aggressive ossifying fibroma, is a benign fibroosseous tumor made of highly cellular fibrous connective tissue. In the current article a case of peripheral ossifying fibroma pof in the anterior maxillary gingiva is highlighted, which histologically showed. However, certain authors have stated that peripheral ossifying fibroma is a variant of central ossifying fibroma and, therefore, a neoplastic process. Other terms used in reference to pof are peripheral cementifying fibroma, peripheral fibroma with cementogenesis, peripheral fibroma with osteogenesis, peripheral fibroma with calcification, calcified or ossified fibrous epulis, and calcified fibroblastic granuloma. A confirmatory diagnosis of peripheral cementoossifying fibroma is made by histopathologic evaluation of biopsy specimens. This is a growth that appears inside the mouth as a small lump on the gum. Cementoossifying fibroma is a benign fibroosseous maxillary tumor belonging to the same category as fibrous dysplasia and. Many of these lesions are difficult to be identified as specific entity only on the basis of typical and consistent histomorphology. Peripheral ossifying fibroma is one such reactive lesion which shows areas of calcification or ossification.
The peripheral ossifying fibroma pof is a reactive gingival overgrowth occurring frequently in the anterior maxilla. Peripheral ossifying fibroma, also known as ossifying fibrous epulis, is a gingival nodule which is composed of a cellular fibroblastic connective tissue stroma which is associated with the formation of randomly dispersed foci of mineralised products, which consists of bone, cementumlike tissue, or a dystrophic calcification. It represents upto 2% of all lesions that are biopsied. A case of cemento ossifying fibroma involving the right mandible is described in a 30 yearold female patient. A novel approach for the treatment of peripheral ossifying fibroma. The peripheral ossifying fibroma pof is the third most common reactive lesion in gingiva, 1 which can be caused by local irritants like ill. Ossifying fibroma is a benign fibroosseous lesion that commonly involves the maxilla. Ossifying fibroma article about ossifying fibroma by the. Other terms used in reference to pof are peripheral cementifying fibroma, peripheral fibroma with cementogenesis, peripheral fibroma with osteogenesis, peripheral fibroma with calcification, calcified. S, ravi david austin department of oral medicine and radiology, rajah muthiah dental college and hospital, annamalai university, chidambaram, tamil nadu, india 608002. Jan 14, 20 the concept of fibroosseous lesions of bone has evolved over the last several decades and now includes two major entities. Peripheral cementoossifying fibroma is a relatively rare tumour classified between fibroosseous lesions. Intraoral ossifying fibromas have been described in the literature since the late 1940s.
The gingival is often the site of localized growths that are considered to be reactive rather than neoplastic in nature. The concept of fibroosseous lesions of bone has evolved over the last several decades and now includes two major entities. Peripheral ossifying fibroma is a localized reactive lesion, which is nonneoplastic and usually restricted to the soft tissues. An unusual presentation of peripheral ossifying fibroma in an. It is most commonly seen between the third and fourth decades of. Central ossifying fibroma cof is a benign osseous neoplasm which consists of highly cellular, fibrous tissue with varying amounts of calcified tissue, which resembles the bone, the cementum or both 1, 2. Peripheral cemento ossifying fibroma is a relatively rare tumour classified between fibroosseous lesions. In contrast to the peripheral ossifying fibroma, the peripheral odontogenic fibroma is a rare lesion. It predominantly affects adolescents and young adults, with peak prevalence between 10 and. Peripheral ossifying fibroma is a gingival growth, usually arising from interdental papilla and occurring frequently in the anterior maxilla. In some cases it may be what is called a peripheral ossifying fibroma. A novel approach for the treatment of peripheral ossifying. Jul 03, 2017 peripheral ossifying fibroma pof is one of the few reactive lesions of the gingiva which are clinically similar in presentation. Excision and repair of the peripheral ossifying fibroma.
These growths are most frequently seen in adolescents but they can occur at any age and they are not cancerous. Peripheral ossifying fibroma pof is a focal, reactive, nonneoplastic tumorlike growth of the soft tissue occurring frequently in the maxillary anterior region, mainly affects females, predominating in the second decade of life. Cementoossifying fibroma radiology reference article. Furthermore, the pof has a propensity to occur in the incisor cuspid area affecting maxilla more than the mandible. Ossifying fibroma definition of ossifying fibroma by. Peripheral ossifying fibroma a clinical and histological.
Peripheral ossifying fibroma is a benign proliferation almost exclusively affecting the gingiva, although a case of pof localized on lingual mucosa has been recorded. Varying amounts of mineralized foci woven and trabecular bone spicules typically are present, some with a psammomatoid appearance globular pattern that may be referred to as. Computed tomography ct detected a fibroosseous lesion that proved to be an ossifying fibroma figure. Peripheral ossifying fibroma is a common lesion of the gingiva with various synonyms like epulis, calcifying fibroblastic granuloma, peripheral cementifying fibroma, and peripheral fibroma with. The aim of this report is to raise awareness of the possibility that cemento ossifying fibroma can transform into osteosarcoma and of the consequent necessity for careful diagnosis and treatment planning. The peripheral ossifying fibroma pof is a relatively uncommon reactive lesion of the gingiva, associated with mineralization and. At 1yr recall, the gingival tissues were healthy with successful healing and no more recurrence. Other terms used in reference to pof are peripheral cementifying fibroma, peripheral fibroma with cementogenesis, peripheral fibroma with osteogenesis, peripheral fibroma with calcification, calcified or ossified fibrous epulis, and calcified. Other terms used to describe this lesion include peripheral ossifying fibroma, peripheral cementifying fibroma and calcified or ossified fibrous epulis. Peripheral ossifying fibroma is thought to be either reactive or neoplastic in nature 2,3. We report a case of a venezuelan female patient with a gigantic peripheral ossifying fibroma in the anterior mandibular region, sized 5. It is more commonly seen in women predilection of 3.
May 31, 2018 a peripheral cemento ossifying fibroma is also known as a peripheral ossifying fibroma, a calcifying fibrous epulis, or a peripheral fibroma with calcification. Peripheral ossifying fibroma in the maxillary arch. Gigantic peripheral ossifying fibroma of the mandible. It has been reported from birth to old age, but peaks in the teenage years. Peripheral ossifying fibroma pof is a reactive lesion of the gingival tissues that predominantly affects women and is usually located in the maxilla anterior to the molars. The aim of the present study was to determine the clinical and radiologic features of of at a tertiary hospital in south africa, assess its management. May 09, 2018 peripheral ossifying fibroma pof is a focal, reactive, nonneoplastic tumorlike growth of the soft tissue occurring frequently in the maxillary anterior region, mainly affects females, predominating in the second decade of life. Aadhirai muthukumaran abstract increase in size is a common feature of gingival disease. Many names have been given to similar lesions, such as epulis, peripheral fibroma with calcification, peripheral ossifying fibroma, calcifying fibroblastic granuloma, peripheral cementifying fibroma, and peripheral fibroma with cementogenesis. Peripheral ossifying fibroma pof is a nonneoplastic enlargement of gingiva that is classified as a reactive hyperplastic inflammatory lesion. What is peripheral ossifying fibroma peripheral ossifying fibroma is a benign swelling of the gum, most commonly seen in teenagers and young adults. In this case report, we present the clinical, radiological, and histopathological features of peripheral ossifying fibroma of an abnormally large size. Peripheral ossifying fibroma is a common solitary gingival overgrowth thought to arise from the gingival corium, periosteum or periodontal ligament. When lesions in soft tissue reach the gingival margin, they can produce aesthetic defects during its permanence and after its removal.
Peripheral ossifying fibroma pof is a lesion of the gingival tissues representing up to 2% of all oral lesions that are biopsied. Peripheral ossifying fibroma a clinical evaluation of 4 pediatric cases. Many names have been given to similar lesions, such as epulis, peripheral fibroma with calcification, pof, calcifying fibroblastic granuloma, peripheral cementifying fibroma, peripheral fibroma with cementogenesis and peripheral cementoossifying fibroma. An ossifying fibroma can be one of two different types of tumor, or growth.
Many names have been given to similar lesions, such as epulis, peripheral fibroma with calcification, pof, calcifying fibroblastic granuloma, peripheral cementifying fibroma, peripheral fibroma with cementogenesis and peripheral cemento ossifying fibroma. It can be confused with the peripheral ossifying fibroma. The term epulis includes a series of reactive gingival lesions often produced by irritating agents. Ossifying fibroma of is one of the most frequent of the 3 fibroosseous lesions of the jaws and has had an inconstant recurrence rate. Pofs consist of one or more mineralized tissues, including bone, cementumlike material, or dystrophic calcification within a matrix of cellular fibroblastic tissue.
Ossifying fibroma of the ethmoid sinus included in the group of benign fibroosseous lesions are fibrous dysplasias and ossifying fibromas. Peripheral ossifying fibroma is an inflammatory growth of the gums developing in response to plaque and other associated local factors favoring plaque accumulation and originating from the cells. It is derived from cells of the periodontal ligament and is usually classified as a reactive hyperplasia but sometimes as a benign neoplasm. A case report with 1year followup shaswata karmakar, rashmi srinath, shobha prakash department of periodontics and implantology, college of dental sciences, davangere, karnataka, india. There was considerable confusion in the terminology used in the literature. It is a reactive gingival lesion that is believed to arise from cells of the periodontal ligament or periosteum. Peripheral ossifying fibroma pof is a relatively uncommon gingival growth that is considered to be. Kumar sk, ram s, jorgensen mg, shuler cf, sedghizadeh pp. Juvenile ossifying fibroma of the calvaria radiographics. Unusually largesized peripheral ossifying fibroma john rr.
The diagnosis is usually established on the basis of the clinical findings, with few clinical differences noted among the different disorders included under this term. The histological study of the specimen after simple resection confirmed the diagnosis of peripheral ossifying fibroma. Peripheral ossifying fibroma is an inflammatory growth of the gums developing in response to plaque and other associated local factors favoring plaque accumulation and. Mar 30, 2017 intraoral ossifying fibromas have been described in the literature since the late 1940s. It was first described as relatively uncommon, solitary, nonneoplastic gingival growth by eversol and robin. Peripheral ossifying broma occurs mostly in craniofacial bones and categorized into two types central and peripheral. First description of ossifying fibroma was given by menzel in 1872 while the term was given by montgomery in 1927. Peripheral ossifying fibroma is a reactive lesion found on the gingiva and nonneoplastic in nature. Coverage root after removing peripheral ossifying fibroma. Ossifying fibroma definition of ossifying fibroma by the.
Peripheral ossifying fibroma pof is one of the few reactive lesions of the gingiva which are clinically similar in presentation. In the current article a case of peripheral ossifying fibroma pof in the anterior maxillary gingiva is highlighted, which histologically. A definitive surgical protocol has not yet been published. A peripheral cementoossifying fibroma is also known as a peripheral ossifying fibroma, a calcifying fibrous epulis, or a peripheral fibroma with calcification. Pof or peripheral cementoossifying fibroma is the peripheral counterpart of the central cementoossifying fibroma. Pof has also been described by various synonyms such as peripheral cemento ossifying fibroma, peripheral odontogenic fibroma podf with cementogenesis, peripheral fibroma with osteogenesis, peripheral fibroma with calcification, fibrous epulis, calcifying fibroblastic granuloma, etc. This paper is a case report of a peripheral ossifying fibroma removal in the interproximal area of teeth 21 and 22 in addition to root coverage of the.
Pof typically presented as a solitary, slow growing nodular mass that is either pedunculated or sessile. Mar 24, 2019 cementoossifying fibroma a case report. Nov 06, 2011 peripheral ossifying fibroma pof is a nonneoplastic entity, which occurs on the gingiva in response to trauma or irritation. Mar 30, 2020 an ossifying fibroma can be one of two different types of tumor, or growth. Peripheral ossifying fibroma pof is a relatively uncommon, probably reactive gingival overgrowth. It originates in the cells of the periodontal ligament and is more common in children and young adults. Peripheral ossifying fibroma associated with a neonatal tooth. Peripheral ossifying fibroma pof has been cited in the literature under various names such as cemento ossifying fibroma, peripheral fibroma with osteogenesis, peripheral odontogenic fibroma, calcifying fibroblastic. Peripheral ossifying fibroma a case report article pdf available in journal of the indian dental association 5. Pdf peripheral ossifying fibroma a case report semantic. Peripheral ossifying fibroma pof is a lesion of the gingival tissues 15 representing up to 2% of all oral lesions that are biopsied 1. Periodontal plastic surgery allows the correction of the gingival contour using different techniques.
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